St. Louis’s strong tradition of civic collaboration gives nonprofits, foundations, cultural institutions, associations, and community organizations an outsized role in addressing the region’s most complex challenges.

Mid-market technology firms can help these organizations strengthen donor and constituent systems, modernize grant management, measure impact, protect sensitive information, automate administrative work, and expand service capacity without requiring large internal technology teams.

Sector by the Numbers (MSA):

• 168 mid-to-large employers
• 25.5K employees
• $926M annual revenue
• $4.8M median revenue
• 2.5% share of jobs

As St. Louis modernizes aging infrastructure while investing in new districts, facilities, transportation systems, and major developments, technology will directly shape the region’s next era of growth.

Regional providers bring expertise in construction-management platforms, building information modeling, geospatial tools, connected facilities, digital twins, project analytics, safety systems, smart-building technology, and lifecycle asset management.

Sector by the Numbers (MSA):

• 369 mid-to-large employers
• 61.0K employees
• $27.0B annual revenue
• $8.9M median revenue
• 5.0% share of jobs

St. Louis’s economy depends on complex energy, water, telecommunications, transportation, and public-service systems that must remain secure, reliable, and resilient.

Regional technology firms are positioned to support grid and network modernization, operational technology security, asset monitoring, field-service systems, predictive maintenance, outage response, data integration, and the intelligent infrastructure required for continued regional growth.

Sector by the Numbers (MSA):

• 136 mid-to-large employers
• 42.6K employees
• $14.2B annual revenue
• $22.5M median revenue
• 5.1% share of jobs

St. Louis pairs a deep banking, investment, insurance, and payments base with the Federal Reserve Bank of St. Louis and an emerging fintech venture ecosystem, creating a strong platform for innovation in money, risk, privacy, and financial infrastructure.

TechSTL’s mid-market companies are equipped to help financial organizations modernize payments, strengthen fraud and cyber defenses, automate compliance, improve risk intelligence, connect legacy systems, govern sensitive data, and deliver more seamless digital customer experiences.

Sector by the Numbers (MSA):

• 190 mid-to-large employers
• 64.4K employees
• $8.5B annual revenue
• $13.1M median revenue
• 7.5% share of jobs

Because the St. Louis metro spans two states, 15 counties, and a highly distributed network of municipalities and public agencies, technology is essential to making regional services more connected, secure, efficient, and accessible.

TechSTL’s experienced providers can help agencies modernize legacy systems, protect sensitive data, improve digital constituent services, connect departmental information, strengthen public-safety technology, and automate internal processes.

Sector by the Numbers (MSA):

• 154 mid-to-large employers
• 61.5K employees
• $1.2B annual revenue
• $30.9M median revenue
• 7.5% share of jobs

St. Louis is home to major health systems, hospitals, clinics, senior-care providers, behavioral-health organizations, and other institutions delivering care across the region. These organizations face growing pressure to improve access, reduce costs, protect sensitive data, modernize operations, and respond to rapid changes in workforce, reimbursement, and patient expectations.

TechSTL’s mid-market companies help healthcare systems and care providers strengthen cybersecurity, connect fragmented data, modernize clinical and administrative workflows, deploy responsible AI, improve patient engagement, and build more efficient, resilient models of care.

Sector by the Numbers (MSA):

• 477 mid-to-large employers
• 158.9K employees
• $12.8B annual revenue
• $4.6M median revenue
• 17.5% share of jobs

With a dense network of universities, colleges, technical schools, medical campuses, and research institutions, St. Louis has a powerful foundation for discovery, talent development, and workforce reinvention.

Local technology companies can support these institutions with cybersecurity, research-data infrastructure, cloud modernization, AI-enabled learning, student-success systems, enrollment technology, grant administration, and stronger connections between academic discovery and industry.

Sector by the Numbers (MSA):

• 104 mid-to-large employers
• 47.9K employees
• $617M annual revenue
• $4.5M median revenue
• 5.7% share of jobs